Understanding the Associations Between Romantic Relationship Conflict, Psychophysiological Responding and Alcohol Misuse Among Emerging Adults

Not yet recruiting

• Conditions: Heavy Episodic Drinking

• Registration Number: NCT06976528
• Lead Sponsor: New York University

Brief Summary

Emerging Adults (EA) engage in heavy episodic drinking (HED) at a greater quantity and frequency than any other time in their lives, which may lead to significant short- and long-term consequences. Although much is known about the influence of peers in EA alcohol use, there is a dearth of research examining the ways in which romantic partners influence EA drinking behaviors. The proposed study bridges a crucial gap in the existing literature by examining behavioral and physiological risk and resilience factors in the acute link between EA relationship conflict and alcohol consumption. EA couples will engage in two conflict resolution tasks interspersed with two puzzle tasks and two alcohol administration procedures. Because high frequency heart rate variability (HF-HRV) is associated with alcohol use and emotion regulation during stressful experiences, HF-HRV and other physiological data will be collected throughout the laboratory procedures.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-05
• Study First Submitted: 2025-05-08
• Study First Submitted QC: 2025-05-08
• Last Update Submitted: 2025-05-08
• Study First Posted: 2025-05-16
• Last Update Posted: 2025-05-16
• Study Start: 2025-07
• Primary Completion: 2029-07
• Study Completion: 2030-07

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

Age 21-29 years old, must be in a committed romantic relationship of at least 3 month duration, must report at least 2 HED episodes in the past 30 days (5 or more drinks within 2 hours for males, 4 or more drinks within 2 hours for females), must self-report that they have - on at least three occasions during the past year - consumed a quantity of alcohol that is equal to or greater than the standard dose administered for their weight inthe laboratory

Exclusion Criteria

1. Meeting DSM-5 criteria for a history of or current neurological, psychotic, or bipolar disorders
2. History of self-reported head trauma requiring medical treatment
3. Body weight exceeding 250 pounds
4. Current enrollment in treatment or seeking treatment for a substance or alcohol use disorder
5. Current suicidal or homicidal intent
6. Serious cardiovascular health conditions (e.g. pacemaker, cardiac arrhythmia, hypertension) that may alter normative cardiac functioning
7. Treatment on medications such as lithium, methadone, alpha or beta blockers or cholinergic/anticholinergic medications likely to confound normative cardiovascular responding or response to alcohol administration. Stimulant or benzodiazepine medication use is permissible provided participants do not take medication on the day of study participation
8. Severe and/or unilateral IPV in the past 6 months
9. Pregnancy or breastfeeding
10. Severe Alcohol Use Disorder (as defined by the DSM-5)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
High frequency heart rate variability (HF-HRV)	~8 hours	High frequency heart rate variability (HF-HRV) is a neurally-derived measure of parasympathetic activity that may partially explain the association between stressful relationship conflict and alcohol misuse. HF-HRV is a measure of the variability in interbeat intervals, or the time in between beats of the heart.