NCT03847116已完成不适用
Association of Light-to-moderate Alcohol Consumption With Risk of Type 2 Diabetes Mellitus in Individuals With Nonalcoholic Fatty Liver Disease
Ningbo No. 1 Hospital1 个研究点 分布在 1 个国家目标入组 14,014 人开始时间: 2009年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 14,014
- 试验地点
- 1
- 主要终点
- Light-to-moderate alcohol consumption (LMAC) and risk of prevalent type 2 diabetes mellitus (T2DM)
研究概览
简要总结
This study explored the cross-sectional and prospective associations between light-to-moderate alcohol consumption (LMAC) and risk of type 2 diabetes mellitus (T2DM) in individuals with nonalcoholic fatty liver disease (NAFLD).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •aged 18 years or above
- •undergoing annual health examinations in 2009 in Zhenhai Lianhua Hospital, Ningbo, China.
- •informed about the study
排除标准
- •female participants;
- •missing data on ultrasound, alcohol consumption, and T2DM status;
- •alcohol consumption > 210 g per week, and binge drinkers;
- •with evidence of other liver diseases including viral hepatitis, autoimmune hepatitis, and drug-induced liver disease.
结局指标
主要结局
Light-to-moderate alcohol consumption (LMAC) and risk of prevalent type 2 diabetes mellitus (T2DM)
时间窗: cross-sectional analyses in 2009
Fatty liver was assessed by ultrasound. T2DM was defined as the presence of any of the following conditions based on American Diabetes Association criteria: (1) fasting plasma glucose (FPG) ≥ 7.0 mmol/L; (2) hemoglobin A1c (HbA1c) ≥ 6.5%; (3) self-reported clinician-diagnosed T2DM.
次要结局
- LMAC and incident risk of T2DM(9-year cohort observation)
研究者
研究点 (1)
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