Pregnancy Rate by HCG Administration Versus Urinary LH Surge Method in Patients Undergoing IUI
- Registration Number
- NCT02638285
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
To compare pregnancy rate by Human Chorionic Gonadotropin (HCG) administration and urinary Luteinizing Hormone (LH) surge method for insemination in patients undergoing Intrauterine Insemination (IUI) at Montaserieh infertility center.
The present study comprised 309 infertile women candidate for IUI, randomly divided into LH surge and HCG groups (assign the number for each patient, odds number for LH and even number for HCG group). All patients were subjected to baseline ultrasound and received clomiphene citrate before undergoing serial transvaginal sonography. LH was measured using LH kit when 2-5 follicles (18-20 mm) appeared in LH surge group, and if positive, IUI was performed after 24 hours. In HCG group, the patients received HCG 1000 units and underwent IUI after 36 hours. The pregnancy rate was then compared in LH and HCG groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Not specified
- Target Recruitment
- 86
- infertile women candidate for IUI
- women with negative urinary LH surge which required HCG administration,
- those with more than 5 follicles who had to use LH kit and not receive HCG to avoid ovarian hyperstimulation.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description clomiphene citrate LH clomiphene citrate LH group Clomiphene LH group HCG group Clomiphene HCG group HCG group HCG HCG group clomiphene citrate HCG clomiphene citrate LH group LH LH group
- Primary Outcome Measures
Name Time Method pregnancy rate Two weeks after IUI
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Health Policy Research Center
🇮🇷Shiraz, Fars, Iran, Islamic Republic of