NCT01922323已完成不适用
Metabolomics of Liver Regeneration Following Partial Hepatectomy in Healthy Living Liver Donors
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Characterized Metabolic Changes during liver regeneration
研究概览
简要总结
The PI will study metabolism during liver regeneration in living liver donors
详细描述
Samples of blood and urine will be collected from study participants at defined timepoints. The samples will be evaluated to study the metabolism of the regenerating liver after a portion of the liver has been donated from a living donor.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Potential donor must be in excellent medical and psychological health.
- •Potential donor must be between the ages of 18 and
- •Must have a compatible blood type to the recipient.
- •Must have health care coverage for non-donor related health issues that arise post donation
- •Recipient and donor must have compatible body size.
- •Donors Body Mass Index (BMI) must be less than
- •All previous donor abdominal surgeries will be reviewed on a case by case basis by the surgeon.
排除标准
- •Positive blood test for Human Immunodeficiency Virus, Hepatitis C virus, Hepatitis B virus
- •The size of the donor liver is not large enough to safely resection and still retain enough volume to function normally after the surgery.
- •Liver biopsy show liver cirrhosis or early stages of HCC.
结局指标
主要结局
Characterized Metabolic Changes during liver regeneration
时间窗: one year after donation
次要结局
未报告次要终点
研究者
研究点 (1)
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