Does epidural analgesia affect outcome after lower limb bypass surgery?

Not Applicable

Completed

• Conditions: Peripheral Vascular Disease; Surgery - Other surgery; Anaesthesiology - Pain management

• Registration Number: ACTRN12609000409279
• Lead Sponsor: St. Vincent's Hospital Melbourne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-06-03
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 320

Inclusion Criteria

Lower limb arterial bypass surgery where the distal vascular anastomosis is below the level of knee joint

Exclusion Criteria

Contraindications to epidural analgesia such as coagulopathy, neurological conditions affecting the lower limbs, orthopaedic or septic complications at proposed epidural insertion site; intolerance of parenteral analgesics

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Vascular Graft Patency.<br>Graft surveillance is performed at least 4 hourly throughout the hospital admission by assessment of pulses and, in the absence of a pulse, Doppler ultrasound. Graft failure is defined as the requirement for thrombectomy, regrafting or unexpected amputation.<br>Method of assessment includes patient history review for the duration of inpatient admission. Following discharge, histories are reviewed for information from outpatient appointments where available. Where this is incomplete or unavailable, patients and/or their primary care physician are contacted by telephone call.[30 days, 6 months from the day of surgery; graft complications within 30 days define early graft failure; graft complications between 30 days and 6 months define late graft failure.]

Secondary Outcome Measures

Name	Time	Method
Any other postoperative medical or surgical morbidity, defined as presentation of a new illness or exacerbation of a pre-existing illness. <br>Method of assessment includes patient history review for the duration of inpatient admission. Following discharge, histories are reviewed for information from outpatient appointments where available. Where this is incomplete or unavailable, patients and/or their primary care physician are contacted by telephone call.[30 days, 6 months from the day of surgery; morbidity within 30 days defines early morbidity; morbidity between 30 days and 6 months defines late morbidity.]