Urodynamics and Clinical Factors That Are Associated With Bladder Over-sensitivity
- Conditions
- Bladder Outlet ObstructionBenign Prostate EnlargementBladder DiseaseStress Incontinence (Female) (Male)Overactive Bladder Syndrome
- Registration Number
- NCT03486639
- Lead Sponsor
- Assaf-Harofeh Medical Center
- Brief Summary
Urodynamic examination evaluates storage and empting phases of the urinary bladder. It enables the clinician to correlate physiologic findings to patients' complains. The data gathered during the examination divided to storage and empting.
During the storage phase, bladder sensation is measured while the bladder is filled with sterile water. During years of practice, we noticed that early sensation (bladder over-sensitivity) is occasionally associated with bladder outlet obstruction (as demonstrated in the emptying phase of the examination.
- Detailed Description
The study includes patients who were referred to Urodynamics examination due to lower urinary tract symptoms. There is no actual intervention during the examination. Though, patients are asked to fill an International prostate symptom score (IPSS-questionnaires).
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 330
- All patients refered to Asaf HaRofeh Medical Center for Urodynamic examination
- Inability to sign an informed concent
- Administration of analgesics 8 hours prior to the examination
- Known urethral stricture
- Chronic bladder or urethral pain
- Active cystitis
- Permanent urinary catheter
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Early sensation during the filling phase During the urodynamic examination Bladder oversensitivity (early sensation), a diagnosis made by symptoms and urodynamic investigations. Defined as an increased perceived bladder sensation during bladder filling with specific cystometric findings of: (i) an early first desire to void; (ii) an early strong desire to void, which occurs at low bladder volume; (iii) a low maximum cystometric bladder capacity; no abnormal increases in detrusor pressure.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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Trial Locations
- Locations (1)
Assaf Harofe Medical Center
🇮🇱Be'er Ya'aqov, Israel
Assaf Harofe Medical Center🇮🇱Be'er Ya'aqov, IsraelGuy Verhovsky, M.DContact089779409guy.verchovsky@gmail.comKobi Stav, M.DContact089779409stavkobi@gmail.comGuy Verhovsky, MDPrincipal InvestigatorKobi Stav, MDSub Investigator