Comparison of Postoperative Pain Management in Patients Undergoing Laparoscopic Colorectal Surgery Under Enhanced Recovery After Surgery (ERAS) Program, Laparoscopic Colorectal Surgery Without ERAS and Open Colorectal Surgery

• Conditions: Postoperative Pain
• Interventions: Drug: Celecoxib

• Registration Number: NCT04997174
• Lead Sponsor: Prince of Songkla University

Brief Summary

This is a retrospective study to compare postoperative pain intensity in patients going laparoscopic colorectal surgery with Enhanced Recovery after Surgery (ERAS), without ERAS and open colorectal surgery.

Detailed Description

This study is a matched case-control study. Control patients will be matched to ERAS cases in a 1:1:1 ratio (laparoscopic surgery with ERAS protocol : laparoscopic surgery without ERAS protocol : open surgery).

Study Timeline

• Study First Submitted: 2021-07-30
• Study First Submitted QC: 2021-07-30
• Study First Posted: 2021-08-09
• Status Verified: 2021-10
• Study Start: 2021-10
• Last Update Submitted: 2021-10-09
• Last Update Posted: 2021-10-18
• Primary Completion: 2021-12
• Study Completion: 2022-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 162

Inclusion Criteria

• Patients undergoing colorectal surgery under ERAS program and those with the same sort of laparoscopic surgery without ERAS program as well as those with open colorectal surgery with complete required recorded data.

Exclusion Criteria

• 1. Patients with incomplete required data on record.
• 2. Those with any major intraoperative or postoperative complications.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
ERAS	Celecoxib	Patients undergoing laparoscopic colorectal surgery with ERAS

Primary Outcome Measures

Name	Time	Method
Pain intensity	Until discharge (5-7 days)	Pain score (Verbal Numerical Rating Scale: VNRS) after surgery, VNRS consists of 0-10, where 0 means no pain and 10 means worst pain imaginable

Secondary Outcome Measures

Name	Time	Method
Opioid	Until discharge (5-7 days)	Amount of postoperative opioid consumption

Trial Locations

Locations (1)

Sasikaan Nimmaanrat; 🇹🇭 Hat Yai, Songkhla, Thailand