Transmural Collaborative Care: Depression and Anxiety disorders with concomitant physical symptoms.
- Conditions
- Physical symptoms, major depressive disorder, generalized anxiety disorder, panic disorder.Lichamelijke klachten, depressie, gegeneraliseerde angststoornis, paniekstoornis.
- Registration Number
- NL-OMON23655
- Lead Sponsor
- GGZ BreburgPostbus 7705000 AT TilburgThe NetherlandsTel: +31 (0)88 0161616Fax: +31 (0)88 0161199info@ggzbreburg.nlBezoekadres: Lage witsiebaan 4, 5042DA Tilburg, The Netherlands
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- Not specified
- Target Recruitment
- 174
Of the referred patients, all patients that present with both five physical symptoms and a common mental disorder, namely MDD, GAD or PD, are eligible for the study. MDD is operationalized as a score of 10 or more on the Patients Health Questionnaire depression subscale (PHQ9) on the ROM; GAD and PD are operationalized as a score of 10 or more on the GAD7, and we speak of increased physical symptoms when the patient reports five or more physical symptoms on a validated self-report questionnaire (Physical Symptoms Questionnaire, in Dutch ‘Lichamelijke Klachten Vragenlijst’; LKV) as that number of symptoms was found to be associated with poor functioning by Escobar e.a. The diagnosis of MDD, GAD or PD should be confirmed in the clinical interview that follows the ROM. If the diagnosis is not confirmed in the clinical interview, but the patient does have a score of 10 or more on the PHQ9 or GAD7, the patient will also be included. The data of these patients will form a subgroup in the analysis. All the described patients are asked informed consent and if they agree, are enrolled in the study. Although women suffer from (medically unexplained) physical symptoms, MDD and anxiety disorders more often than men, both sexes will be sufficiently represented in the sample to consider gender as a variable in the analysis. The same holds for age and cultural background.
Patients are excluded from the study if they are less than 18 years old, have insufficient knowledge of Dutch to fill in the questionnaires, or are suicidal, psychotic or suffering from dementia.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Baseline measurements: <br /><br>The PHQ9, the GAD7 and the LKV. The Mini International Neuropsychiatric Interview (MINI) for classification of symptoms. <br /><br>Primary outcome measure is reduction of physical symptoms as measured by the LKV, as this is considered crucial to attain improvement on the concomitant common mental disorder as well. <br /><br>The CBS questionnaire will be used to distinguish between medically explained and medically unexplained physical symptoms.
- Secondary Outcome Measures
Name Time Method