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Insomnia and Rumination in Late Pregnancy and the Risk for Postpartum Depression

Not Applicable
Completed
Conditions
Insomnia
Post Partum Depression
Interventions
Behavioral: dCBTI
Behavioral: Sleep Education
Registration Number
NCT03596879
Lead Sponsor
Henry Ford Health System
Brief Summary

The primary objective of the proposed research is to determine whether prenatal insomnia and ruminative thinking predict severity of postpartum depression (PPD) symptoms. Additionally, the investigators will also determine the effectiveness of digital/internet-based Cognitive Behavioral Therapy for Insomnia (dCBTI) in reducing the risk for PPD.

Detailed Description

The purpose of this study is to 1) explore the relationship between prenatal insomnia, ruminative thinking and the severity of PPD symptoms. and 2) determine the effectiveness of Digital Cognitive Behavioral Therapy (dCBTI) in reducing the risk for postpartum depression in pregnant mothers entering into their third trimester. dCBTI is an online form of Cognitive Behavioral Therapy (CBT) that is used with people who experience trouble sleeping at night (insomniacs). As pregnant women are especially vulnerable to sleep problems during this period, this study will help us determine whether dCBTI is helpful in improving sleep and reducing the risk for PPD in this population.

Pregnant women entering their third trimester will be recruited from the Henry Ford Health System through the HFHS Electronic Medical Record (EPIC). They will receive an email from study personnel describing the study, and encouraged to schedule a phone call to discuss study details. Participants will then complete a consent and an online screening survey. Upon meeting inclusion criteria, participants will complete weekly surveys and randomized into one of 2 active online insomnia treatment conditions. Each treatment involves 6 weekly "sessions" which each take up to 20 minutes to complete.

Subjects will complete weekly online surveys beginning at week 30 of pregnancy, and continuing through 6 weeks after giving birth.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
91
Inclusion Criteria
  • Must be entering their 3rd trimester of pregnancy
  • Must deny any concerns or indications of a high risk pregnancy associated with increased risk for the mother or fetus for negative health outcomes
Exclusion Criteria
  • Age < 18 years old
  • Bipolar or seizure disorders (due to risk in CBTI)
  • Known sleep disorders other than insomnia (eg narcolepsy, restless legs syndrome, obstructive sleep apnea)
  • Women already in their 3rd trimester
  • Women who are not pregnant
  • Women with high risk pregnancy

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
dCBTIdCBTIOnline access to the digital CBTI program Sleepio.
Sleep EducationSleep EducationWeekly email messages with sleep hygiene recommendations.
Primary Outcome Measures
NameTimeMethod
Improvement in Sleep - Insomnia Severity IndexYear 1

The Insomnia Severity Index (ISI) is a commonly used self-report measure of insomnia symptoms that has been validated for use in community samples and clinical trials. The ISI scores range from 0-28, with a higher score indicating a greater severity of insomnia.

Prevention of Postpartum Depression Symptoms - Edinburg Postnatal Depression Scale (EPDS)Year 1

The Edinburgh Postnatal Depression (EPDS) is the most widely used depression measure in both pregnant and postnatal women. It is validated for use in community samples and clinical trials. The EPDS scores range from 0-30, with a higher score indicating a greater severity of depression.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Henry Ford Medical Center

🇺🇸

Novi, Michigan, United States

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