ISRCTN17616237Active, not recruiting未知
External phrenic nerve pacing to preserve diaphragm function and improve weaning outcomes: a feasibility study
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Active, not recruiting
- Sponsor
- Sir Run Run Shaw Hospital
- Enrollment
- 60
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •1. Patients with acute respiratory failure requiring invasive mechanical ventilation
- •*Incorporated within 48 hours after the establishment of the artificial airway
- •2. Estimated mechanical ventilation time >72 hours
- •3. Aged over 18 years old
Exclusion Criteria
- •1. Pneumothorax or mediastinal emphysema
- •2. Acute myocarditis, severe arrhythmia
- •3. Neuromuscular diseases that may affect weaning, including myasthenia gravis, motor neuron disease, and congenital myopathy
- •4. Hemodynamic instability (mean arterial pressure <60 mmHg and norepinephrine >0.2 ug/kg/min)
- •5. Paroxysmal sympathetic hyperactivity syndrome
- •6. Even chest
- •7. Pregnancy
- •8. Fitted with a pacemaker/implantable defibrillator
- •9. Applying neuromuscular blockers (NMBAs) within the past 6 hours
- •10. History of neck radiation therapy or neck surgery
- •11. Cancer of the neck and lung
- •12. Unable to obtain accurate diaphragm ultrasound results
Investigators
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