Dutch Antibiotics in Respiratory syncytial virus infection Trial
Completed
- Conditions
- Respiratory tract infection, Bronchiolitis, Pneumonia, Respiratory Syncytial Virus (RSV)RespiratoryRespiratory tract infection
- Registration Number
- ISRCTN86554663
- Lead Sponsor
- VU University Medical Centre (The Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
Children less than 24 months of age with a virologically confirmed diagnosis of RSV LRTD, defined by a first episode of dyspnoea with increased body temperature (more than 37.5°C), and/or cough, coryza, wheezing, crackles on pulmonary auscultation.
Exclusion Criteria
1. Age more than 24 months
2. Children presenting with apnoea with signs of lower respiratory tract disease
3. Nosocomial RSV infection
4. Antibiotic treatment less than seven days before hospital admission
5. Absence of informed consent by parents or legal representatives
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of hospitalisation
- Secondary Outcome Measures
Name Time Method 1. Proportion and duration of oxygen therapy<br>2. Proportion and duration of bronchodilator therapy<br>3. Duration of tachypnoe (more than 40 breaths/min)<br>4. Duration of fever (more than 37.5°C)<br>5. Duration of impaired feeding<br>6. Number of infants referred to Paediatric Intensive Care Unit (PICU)<br>7. Course of RSV score