JPRN-UMIN000043345
Completed
未知
Development and validation of a clinical prediction model for psychotic relapse within 12 months after discharge in people with schizophrenia - Development and validation of a clinical prediction model for psychotic relapse within 12 months after discharge in people with schizophrenia
Department of Health Promotion and Human Behavior, Kyoto University School of Medicine0 sites805 target enrollmentFebruary 20, 2021
ConditionsSchizophrenia and related disorders
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Schizophrenia and related disorders
- Sponsor
- Department of Health Promotion and Human Behavior, Kyoto University School of Medicine
- Enrollment
- 805
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The significant predictors were the number of previous hospitalizations (HR 1.42, 95% CI 1.22-1.64) and the current length of stay in days (HR 1.31, 95% CI 1.04-1.64). In model development for relapse, Harrells c-index was 0.59 (95% CI 0.55-0.63). The internal and internal-external validation for rehospitalization showed Harrells c-index to be 0.64 (95% CI 0.59-0.69) and 0.66 (95% CI 0.57-0.74), respectively. The calibration plot was found to be adequate
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •Patients with the following conditions will be excluded: \- Those who had been enrolled in this study with a previous episode of hospitalisation due to psychosis (i.e. a patient cannot be enrolled more than once during the study period) \- Those with substance/medication\-induced psychosis \- Those with psychosis due to another medical condition, including peri\-and postpartum psychosis and psychosis in dementia \- Those with diagnosis in the inclusion criteria whose admission are not due to psychosis as judged by one of investigators \- Those with diagnosis in the inclusion criteria with which one of investigators disagree due to the lack of sound reasoning \- Those discharged from a non\-acute ward \- Those with a plan to be readmitted in the short period of time \- Those with ambiguous diagnosis as judged by one of investigators \- Those discharged to another psychiatric hospital \- Those discharged to medical hospital
Outcomes
Primary Outcomes
Not specified
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