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临床试验/NCT05852652
NCT05852652已完成不适用

The Effect of Combination Between Cryolipolysis and Aerobic Exercise in Reducing Abdominal Adiposity in Obese Subjects

Cairo University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2022年12月12日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
40
试验地点
1
主要终点
abdominal skin fold

研究概览

简要总结

The purpose of the study is To investigate the adding effect of Cryolipolysis to aerobic exercise with low caliorie diet on waist-to-hip ratio , ultrasonography, body mass index and skin fold of subcutaneous fat tissue in abdominal adiposity in obese subjects

详细描述

Obesity is a serious disease marked by an increase in body weight of at least 20% over the ideal weight due to an accumulation of body fat.

The prevalence of obesity has hit epidemic levels over the past few decades, and numerous obesity-related illnesses, including heart conditions, certain types of cancer, and diabetes, have risen concurrently. Weight loss through lifestyle modification, including a hypocaloric diet and/or increased physical exercise, along with behavioural techniques to support these changes, is the basis for treating or preventing these diseases through therapeutic intervention. Such methods rarely result in an obese person reaching a normal body weight because the typical weight reduction from lifestyle change is between 5 and 10% of baseline weight.

Recently, studies have used numerous devices, including cavitation, radiofrequency, cryolypolysis, and other many devices, according to the World Health Organization, to solve this issue.

The FDA has approved the cryolipolysis device for cutaneous cooling as well as a number of other uses. Cryolipolysis is a novel non-invasive technique for the selective reduction of fat cells with controlled, localised cooling.

Clinicians use the waist measurement and waist-to-hip ratio to assess abdominal obesity. These actions have a clear correlation to many vascular diseases, including atherosclerosis and the risk of developing acute coronary syndromes.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
35 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Body mass index of the subjects range from (30-40)kg/m2
  • subjects have abdominal adiposity

排除标准

  • patients with liver and kidney diseases
  • patients who have sensitivity to cold
  • patients who have auto-immune disease
  • patients after caesarean section
  • impaired peripheral circulation
  • Raynauds disease
  • pregnant or lactating women within 6 months
  • paroxysmal cold hemogobulinemia
  • individuals who had metabolic derangement such as type 2 dibetes

结局指标

主要结局

abdominal skin fold

时间窗: 2 months

by fat caliper

body mass index

时间窗: 2 months

by equation of world health organization

fat thickness

时间窗: 2 months

by ultrasonography

the waist-to-hip ratio

时间窗: 2 months

by tape measurment

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Heba Ebrahim Elsayed Mohamed

the principle investigator

Cairo University

研究点 (1)

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