ISRCTN84335288已完成未知
A randomised controlled trial investigating the pharmacodynamic effect of TicagrElor Monotherapy on PLATElet reactivity in patients with coronary artery disease
niversity Hospitals Bristol NHS Foundation Trust0 个研究点目标入组 110 人开始时间: 2014年6月23日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 110
研究概览
简要总结
2017 protocol in: https://www.ncbi.nlm.nih.gov/pubmed/29121979 2020 results in https://pubmed.ncbi.nlm.nih.gov/33305660/ (added 14/12/2020)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Patient is treated with dual antiplatelet therapy comprising aspirin and clopidogrel for a minimum of 4 weeks (amended from: for 12 months as of 31/03/2016)
- •2. The patient is scheduled to stop dual antiplatelet therapy and continue with aspirin monotherapy
排除标准
- •1. Contraindication to dual antiplatelet therapy
- •2. Interruption of dual antiplatelet therapy because of bleeding events or increased bleeding risk
- •3. Contraindications to the use of ticagrelor
- •4. Pregnant and or lactating women
- •5. Women with child bearing potential (i.e. not sterilised or not post-menopausal) who are unwilling to use contraception
- •6. Men with a spouse or partner with child bearing potential unless the participant has agreed to use condoms
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