Identification of volatile organic compounds that specify severe asthma phenotypes in Japa
Not Applicable
- Conditions
- Asthma
- Registration Number
- JPRN-UMIN000041913
- Lead Sponsor
- ational Hospital Organization Tokyo National Hospital
- Brief Summary
GC/MS detected 243 VOCs, and 142 frequently detected VOCs were used for statistical analyses. Cluster analysis showed the highest similarities between clusters 3 and 4 (early-onset clusters), followed by the similarities between clusters 1 and 2 (late-onset clusters). Comparisons between clusters 1- 5 and HC revealed 19 VOCs, in which only methanesulfonic anhydride showed p < 0.05 adjusted by false discovery rate. Comparison of these clusters yielded several VOCs showing different trends (p < 0.05).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 245
Inclusion Criteria
Not provided
Exclusion Criteria
1)As a result of medical interview, physical examination or investigation, the physician responsible considers the subject unfit for the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method