Breath Analysis by Ion Mobility Spectrometry

• Conditions: Lung Diseases

• Registration Number: NCT00632307
• Lead Sponsor: Lung Clinic Hemer

Brief Summary

Recognition of disease specific clusters of volatile organic compounds in patients with different lung diseases, using breath analysis with ion mobility spectrometry. Lung diseases of interest are:

* COPD

* tumors

* airway infection

* interstitial lung disease

* sleep apnea Hypothesis: Breath analysis with ion mobility spectrometry can differentiate pulmonary disorders.

Detailed Description

Recruitment of patients with different lung diseases goes on. First sub-group analysis of patients with COPD,lung cancer and sarcoidosis is done in order to create a training set of VOC-clusters for further validation in a bigger population of patients.

Study Timeline

• Study Start: 2006-07
• Study First Submitted: 2008-02-29
• Study First Submitted QC: 2008-03-07
• Study First Posted: 2008-03-10
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-21
• Last Update Posted: 2022-08-24
• Primary Completion: 2023-12-31
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Any patient
• Ages 18-90 years old

Exclusion criteria:

• Patient who are not able to perform an exhalation manoever.

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Identification of diseases specific VOCs	years

Secondary Outcome Measures

Name	Time	Method
Change of disease specific VOCs under therapy	years

Trial Locations

Locations (1)

Lung Clinic Hemer; 🇩🇪 Hemer, Germany