The sensitivity of the pituitary thyrotrophs for ambient thyroid hormone levels.
- Conditions
- sensitivity of the pituitary10043739
- Registration Number
- NL-OMON29857
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 14
Inclusion Criteria
healthy volnteers in the age of 50 to 70 years.
Exclusion Criteria
volunteers with a thyroid dysfunction and/or heart disease
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The first outcome of this study is the relationship of TSH and FT4 for each<br /><br>individual presented in a graphical line. From that we can determine the<br /><br>sensitivity of the pituitary by the slope and baseline value of these lines,<br /><br>which are different for each individual. </p><br>
- Secondary Outcome Measures
Name Time Method <p>The second outcome will be whether we can see inter- and intra-individual<br /><br>differences in sensitivity.</p><br>