The influence of fetal seks on the maternal immunity

Recruiting

• Conditions: preeclampsia; preterm birth; 10027665; 10026908

• Registration Number: NL-OMON43005
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

- healthy
- written informed consent
- 18-40 years
- scheduled for caesarean section (breech position, repeat section, elective)

Exclusion Criteria

- smoking
- immune related disorders
- fever / illness within the last month
- infertility treatment (ovulation induction, IVF-ICSI, intra uterine insemination)
- body mass index <18 or >30
- spontaneous start of labour

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary outcomes of the study will be levels of T cells and macrophage cell<br /><br>subsets. These levels will be analysed and compared between both groups. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcomes will be the effects of maternal blood stimulation by fetal<br /><br>leukocytes. </p><br>