Helminth infection during pregnancy alters immune responses at the fetomaternal interface - HelmVit_Pilotstudy

Institut für Mikrobiologie, Immunologie und Hygiene, Technische Universität München0 sites102 target enrollmentApril 30, 2019

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Haematology and clinical chemistry, Vitamin Status
Sponsor: Institut für Mikrobiologie, Immunologie und Hygiene, Technische Universität München
Enrollment: 102
Status: Completed
Last Updated: last year

No summary available.

Registry

who.int

Start Date

April 30, 2019

End Date

TBD

Last Updated

last year

Study Type

Observational

Sex

Female

Sponsor

Institut für Mikrobiologie, Immunologie und Hygiene, Technische Universität München

•Presence of written consent
•\- Age \> 18 years
•\- feminine
•\- Persons who are legally competent and mentally able to understand and follow the instructions of the study staff.
•\- Patient information and written declaration of consent of the test person
•\- Adequate bone marrow reserve with a peripheral granulocyte count \>1500/µl and platelet count \>40\.000/µl
•\- No condition after recurrent thrombosis or pulmonary embolism
•\- no serious abnormalities during the physical examination
•\- Documentation of known anaphylaxias

•\- Presence of the following autoimmune diseases: Anti\-phospholipid, antibody syndrome, Goodpasture syndrome, Sjögren syndrome, rheumatoid arthritis, lupus erythematosus, sarcoidosis, anti\-neutrophilic cytoplasmic antibodies (ANCA syndrome), scleroderma, chronic polychondritis
•\- The following known immunodepressing diseases: X\-chromosomal A\-?\-Globulinemia, severe combined immunodeficiency (SCID), common variable immunedeficiency (CVID), selective IgA deficiency
•\- known hepatitis B and/or C, HIV, HSV, CMV, syphilis, toxoplasmosis infection
•\- other, severe, active infection
•\- ongoing corticosteroid treatment
•\- transfusion\-dependent anemia
•\- any other disease or medical treatment which, in the opinion of the investigator, would militate against participation in the study, e.g. (pre\-)eclampsia, HELLP syndrome
•\- Persons who have a dependent/labour relationship with the sponsor or investigator.
•\- known cancers currently or in the past