Efficacy of Immunohistochemical Diagnosis with Propionibacterium Acnes-Specific Monoclonal Antibody in Patients with Cardiac Sarcoidosis (Speciemens obtained from autopsy and surgery)- Multicenter Study
Not Applicable
Completed
- Conditions
- Cardiac Sarcoidosis
- Registration Number
- JPRN-UMIN000020054
- Lead Sponsor
- Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
Not provided
Exclusion Criteria
1. Specimens are not suitable for our research or assessment due to poor storage condition. 2.Patients disagree with using specimens in the present study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To investigate the prevalence of specific P.acnesantibody (PAB antibody) in spiciemens obtained from autopsy and surgical resection i patients with cardiac sarcoidosis (CS)
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What is the role of Propionibacterium acnes-specific monoclonal antibodies in cardiac sarcoidosis diagnosis compared to traditional methods?
How effective are immunohistochemical techniques using P. acnes monoclonal antibodies in detecting cardiac sarcoidosis in post-mortem and surgical specimens?
What are the potential molecular mechanisms by which P. acnes antibodies improve diagnostic accuracy for cardiac sarcoidosis?
Are there specific biomarkers associated with P. acnes antibody response in cardiac sarcoidosis patients that could aid in patient selection?
What adverse events have been reported with immunohistochemical diagnosis using P. acnes-specific monoclonal antibodies in cardiac sarcoidosis studies?