Intraoperative adherence of lung protective ventilation in improvement of oxygenation with fixed PEEP and individualised PEEP in post covid patients under general anaesthesia -A randomised controlled trial .

As evidence-based practice has evolved, potential harmful effects of traditional non physiological mechanical ventilation even for a short term have been shown to correlate with increased incidence of ventilator associated lung injury (VILI).  On the other hand, intraoperative lung protective ventilation has been shown to decrease pulmonary complication. The goal of this intervention is to minimize alveolar overdistention, to prevent repeated collapse and reopening of alveoli and to reduce atelectasis which is expected in a traditional ventilation. There have been several trials comparing lung protective strategies with different level of positive end expiratory pressure in various surgeries. This study focuses on comparing individualised PEEP with a fixed PEEP in post COVID patients with an intention to improve intraoperative oxygenation, pulmonary mechanics and early post-operative complication. This study has not been done so far to the best our knowledge.