跳至主要内容
临床试验/CTRI/2025/02/081270
CTRI/2025/02/081270尚未招募不适用

Comparison of Interscalene Block ,Superior Trunk Block and Combined Infraclavicular and Suprascapular Block on Regional Lung Ventilation in Patients Undergoing Shoulder Surgery - Randomized controlled Trial

AIIMS Mangalagiri1 个研究点 分布在 1 个国家目标入组 103 人开始时间: 2025年3月10日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
103
试验地点
1
主要终点
To compare changes in regional lung ventilation and diaphragmatic excursion ratio in interscalene block, superior trunk block and combined infraclavicular brachial and suprascapular nerve block

研究概览

简要总结

Regional anaesthesia has an established role in providing perioperative analgesia for shoulder surgeries. Interscalene block is considered as the gold standard analgesia ,but it holds a high risk of involving phrenic nerve (100%) and thereby hemi diaphragmatic palsy. It can increase morbidity in patients with pre existing respiratory diseases. Several alternatives to the Interscalene block have been proposed in order to avoid the effect on the diaphragm function ,which include Superior Trunk block, Combined Infraclavicular and Suprascapular Nerve block . The phrenic nerve lies in close proximity to the brachial plexus and diverge as it descends over the anterior scalene muscle and as it approaches the root of the neck ,the phrenic nerve usually lies between the subclavian artery and vein , before coursing medially in front of the Internal thoracic artery . Incidence of  phrenic nerve involvement in Superior Trunk block and Combined Infraclavicular and Suprascapular Nerve block ranges between 25 - 76.3% and 6 % respectively. Even though the involvement of phrenic nerve is studied, its influence on respiratory parameters such as regional lung ventilation  is not studied much in any other studies conducted before about these blocks. Electrical Impedence Tomograph is one of the recent lung imaging technique that can provide dynamic information on distribution of regional lung ventilation . EIT possess high temporal and functional resolution allowing the visualisation of dynamic physiological and pathological changes on a breath to breath basis. EIT detect changes in electrical impedence   (i.e changes in gas/fluid ratio ) and describes them in real time,  both visually through images and waveforms and numerically allowing the clinician to monitor the disease evolution .In this we are comparing the effect of Interscalene block, Superior Trunk block and Combined Infraclavicular Brachial and Suprascapular nerve block on regional lung ventilation by using Electrical Impedence Tomograph.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patients of ASA 1-2 of age between 18 years to 65 years of both genders are included in this study.

排除标准

  • patient refusal patients of age less than 18 years and more than 65 years old ASA PS- 3 and above pre existing pulmonary disease previous neck or infraclavicular/suprascapular fossa surgery BMI more than 30kg/m2 contralateral phrenic nerve palsy Obstructive Sleep Apnoea.

结局指标

主要结局

To compare changes in regional lung ventilation and diaphragmatic excursion ratio in interscalene block, superior trunk block and combined infraclavicular brachial and suprascapular nerve block

时间窗: T0-baseline | T1-1 hour after surgery

次要结局

  • To compare the incidence of hemi diaphragmatic palsy(To determine the correlation between regional lung ventilation and diaphragmatic excursion ratio)

研究者

申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Ancy joy

AIIMS Mangalagiri

研究点 (1)

Loading locations...

相似试验