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Residual galactose oxidation capacity and galactosylation abnormalities as possible predictors for galactose tolerance and outcome in patients with galactose-1-phosphate uridyltransferase deficiency

Completed
Conditions
Classical galactosemia
galactose-1-phosphate uridyltransferase deficiency
10027424
10021605
Registration Number
NL-OMON46279
Lead Sponsor
Academisch Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
40
Inclusion Criteria

GALT enzyme activity <15% of healthy controls and/or
two null or severe missence variations in the GALT gene

Exclusion Criteria

individuals with swallowing difficulties will be excluded from part B1 (galactose breath test) of the study

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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