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临床试验/CTRI/2026/04/107306
CTRI/2026/04/107306尚未招募2/3 期

Efficacy of Diode Laser with Calcium Phosphate - Based Varnish and Diode Laser alone among patients with dentine hypersensitivity: A Randomized Controlled Trial

Dr Harsha v1 个研究点 分布在 1 个国家目标入组 46 人开始时间: 2026年6月6日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
46
试验地点
1

研究概览

简要总结

A single-blind randomized controlled trial evaluating the efficacy of diode laser combined with calcium phosphate–based varnish versus diode laser alone in managing dentine hypersensitivity - DH. The study will be conducted at Government Dental College, Thiruvananthapuram, over 18 months, involving 46 participants - 23 per group. Eligible patients aged greater than or egual to18 years with non-carious cervical lesions - Tooth Wear Index score 2 and a VAS score greater than or equal to 2 will be included. Participants will be randomly allocated into two groups: Group A receiving diode laser alone and Group B receiving calcium phosphate–based varnish - MI Varnish followed by diode laser application. Hypersensitivity will be assessed using tactile, air blast, and cold-graded thermal tests, with pain measured through the Visual Analogue Scale immediately after treatment and at 1, 3, and 6 months. Statistical analysis will compare intergroup and intragroup differences. The study aims to determine whether combination therapy offers superior and sustained reduction in dentine hypersensitivity.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 90.00 Year(s)(—)
性别
All

入选标准

  • (i) Patients of either sex with age greater than or equal to 18 years (ii) NCCL, with Tooth wear index score (TWI) 2, not requiring restorative treatment (iii) Preoperative VAS score greater than or equal to 2 (iv) Patients Willing to provide informed consent.

排除标准

  • (1) Teeth with caries, defective restorations, occlusal restorations, chipped teeth (ii) Deep periodontal pockets, periodontal surgery within 3 months, and patients with orthodontic appliance or bridge work (iii) Use of desensitizing paste in the last 3 month (iv) Patient on analgesics (v) Uncontrolled systemic disease.
  • (vi) Persons with mental health issues.
  • (vii) Pregnant or lactating females (viii) Patients undergone bleaching (ix) patients with a proven or suspected milk protein allergy allergy.

研究者

发起方
Dr Harsha v
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

DrHarsha v

Govt.Dental college Thiruvananthapuram

研究点 (1)

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