NCT00957957已完成不适用
Gut Hormone Profiling in Peripheral Blood After Bariatric Surgery in Obese Patients With Type 2 Diabetes
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 主要终点
- Change from baseline in PYY (Peptide YY) measured by ELISA 4 weeks after RYGBP
研究概览
简要总结
This study will examine changes in various gut-derived hormones in obese type 2 diabetic patients before and after elective bariatric surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Documented type 2 diabetes with total disease duration ≤10 years
- •BMI of at least 35 kg/m^2
- •Patient is a surgical candidate for either RYGBP, GBS or vertical sleeve gastrectomy (VSG)
排除标准
- •Any illness that might confound the results of the study or pose additional risk to the patient by participation
- •History of stroke, seizures, or other major neurological disorder
- •History of cancer
- •Patient uses or has used any medication that can alter body weight
- •Patient is unwilling or unable to follow study procedures
结局指标
主要结局
Change from baseline in PYY (Peptide YY) measured by ELISA 4 weeks after RYGBP
时间窗: Baseline and Week 4
次要结局
- Change from baseline in PYY measured by dMS 4 weeks after RYGBP(Baseline and week 4)
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