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A clinical trial to study the effectiveness of combination of two drugs compared to standard single drug treatment in practice for the clearance of filarial infection from the infected individuals

Phase 4
Completed
Conditions
Health Condition 1: null- Lymphatic filariasis Microfilaria carriers
Registration Number
CTRI/2012/02/002467
Lead Sponsor
Indian Council of Medical Research
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
160
Inclusion Criteria

a) Age 18 years and above b) Residing in or around Pondicherry and adjoining Tamilnadu areas. c) with night blood microfilaria counts > 10 mf/ml by membrane filtration. d) No history of treatment for filarial infection for the last two years at least. e) Willing for home visits by the staff of the center. f) Willing to give written informed consent

Exclusion Criteria

a) Body weight less than 30 kg. b) Hepatic or renal disease as evidenced by clinical or biochemical abnormalities. c) concurrent illness like hypertension, diabetes mellitus, cardiac conditions and epilepsy requiring chronic medication. d) Psychiatric illness e). Patients under tetracycline or doxycycline therapy or History of de-worming by albendazole or other anti-helminthics during last one year, f). Pregnancy or lactation

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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