A Pilot Trial of Adalimumab for the Treatment of Osteoarthritis

Phase 2

Completed

• Conditions: Osteoarthritis

• Registration Number: NCT00185562
• Lead Sponsor: Stanford University

Brief Summary

A 12 week trial of Adalimumab in subjects with active erosive inflammatory OA who have ahd an inadequate response to NSAID therapy

Detailed Description

Not available

Study Timeline

• Study Start: 2005-06
• Study First Submitted: 2005-09-09
• Study First Submitted QC: 2005-09-09
• Study First Posted: 2005-09-16
• Study Completion: 2006-01
• Status Verified: 2006-03
• Last Update Submitted: 2006-03-23
• Last Update Posted: 2006-03-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• Age 45 or older, >/=2 tender and 2 swollen joints, inadequate response to NSAID therapy, hand radiographs with evidence of erosive changes, acceptable form of birth control

Exclusion Criteria

• Autoimmune arthropathy, History of psoriasis, Previous TNF therapy, current use of any DMARD, evidence of TB, history of Hep C, B, or HIV

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Safety

Secondary Outcome Measures

Name	Time	Method
20% ACR response

Trial Locations

Locations (1)

Stanford University; 🇺🇸 Stanford, California, United States