Inflammatory Mediators in Sepsis as Indicator for Infection vs Inflammation

University Hospital Tuebingen1 site in 1 country60 target enrollmentDecember 2016

ConditionsInflammation

Overview

Phase: N/A
Intervention: Not specified
Conditions: Inflammation
Sponsor: University Hospital Tuebingen
Enrollment: 60
Locations: 1
Primary Endpoint: Semaphorin 1 to 7 in plasma of septic patients
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Sepsis is still a challenge for clinicians since the detailed pathomechanism are still unknown and until now early markers for sepsis are not defined yet. Immunological pathways and new mediators defined in animal models are not yet investigated in patients with sepsis. Therefore the investigators will measure new mediators in patients with septic shock.

Detailed Description

Semaphorins 1 to 7 will be determined in Blood of patients with early septic shock. Concentration will be compared with blood concentration of postoperative patients suffering systemic inflammatory response syndrome (SIRS).

Registry

clinicaltrials.gov

Start Date

December 2016

End Date

September 2022

Last Updated

4 years ago

Study Type

Observational

Sex

All