NCT02692118Unknown不适用
Inflammatory Mediators in Sepsis as Indicator for Infection vs Inflammation
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Semaphorin 1 to 7 in plasma of septic patients
研究概览
简要总结
Sepsis is still a challenge for clinicians since the detailed pathomechanism are still unknown and until now early markers for sepsis are not defined yet. Immunological pathways and new mediators defined in animal models are not yet investigated in patients with sepsis. Therefore the investigators will measure new mediators in patients with septic shock.
详细描述
Semaphorins 1 to 7 will be determined in Blood of patients with early septic shock. Concentration will be compared with blood concentration of postoperative patients suffering systemic inflammatory response syndrome (SIRS).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Septic Shock
排除标准
- •Age < 18 > 85
- •no consent of caregiver
- •Trauma patients
- •Burn patients
- •Immunosuppression
- •Pregnancy
- •HIV- hepatitis infection
结局指标
主要结局
Semaphorin 1 to 7 in plasma of septic patients
时间窗: 12 months
Concentration of Semaphorin in plasma of 60 sepsis patients \[pg/ml\].
次要结局
未报告次要终点
研究者
研究点 (1)
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