Evaluation of Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Sepsis
- Sponsor
- Universitätsmedizin Mannheim
- Enrollment
- 250
- Locations
- 1
- Last Updated
- 5 years ago
Overview
Brief Summary
During the past years many investigators have focused on the immunological changes in sepsis disease, and great attention has been paid to the development of practicable means of immunomonitoring. Little is known about diagnostic and prognostic vascular biomarkers during the time course of patients with sepsis.
Detailed Description
Primary Outcome Measures: New diagnostic and prognostic markers for septic patients Estimated Enrollment: 300 patients Study Start Date: January 2012 Estimated Study Completion Date: open Estimated Primary Completion Date: open Intervention Details: Procedure: vein puncture comparison of different inflammatory markers in the blood of septic patients
Investigators
Dr. med. Ursula Hoffmann
Principal Investigator
Universitätsmedizin Mannheim
Eligibility Criteria
Inclusion Criteria
- •SIRS-Criteria
- •Proven Infection
- •One sepsis-induced organ-failure
- •Adults \< 18 years old
Exclusion Criteria
- •Pregnancy
- •Blood donor in the last 3 month
Outcomes
Primary Outcomes
Not specified