A clinical research on the treatment of salivation in Parkinson's disease with Gushenshetuo granule under the guidance of Zhou Zhongying's theory of

Phase 1

Recruiting

• Conditions: Parkinson's disease

• Registration Number: ITMCTR2200006620
• Lead Sponsor: The Affiliated Brain Hospital of Nanjing Medical University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1) Age: 30-80 years old, gender not limited, Western medical diagnostic standards refer to the brain bank of British Parkinson's disease association

The United Kingdom Parkinson's disease brain bank

criteria);

2) The diagnostic criteria of traditional Chinese medicine (TCM) are in line with the Chinese medicine for the elderly formulated by the Geriatrics Association of the all China Association of traditional Chinese medicine in 1992

Criteria for diagnosis and evaluation of curative effect of NYF syndrome;

3) Patients with middle and late stage PD with Hoehn Yahr grade between 2.5 and 5;

4) Item 6 of Part II of the Unified Parkinson's Disease Rating Scale (UPDRS ? - 6)

PD patients with a median salivary secretion score of 3 or 4, that is, those with obvious salivary symptoms.

Exclusion Criteria

1) Secondary Parkinson's syndrome;
2) Accompanied by other serious central nervous system diseases;
3) Patients with serious heart, lung and kidney diseases or multiple organ failure;
4) Mental patients;
5) Those with a history of drug abuse or alcohol abuse;
6) Pregnant and lactating women.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Chinese medicine symptom score scale for PD;Clinical Scale for PD Salivation ;