Urine N-telopeptide, Serum Vit D, Parathormone and Calcium Levels in Hyperemesis Gravidarum

Kayseri Education and Research Hospital1 site in 1 country60 target enrollmentJune 2016

ConditionsHyperemesis Gravidarum

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Hyperemesis Gravidarum
Sponsor: Kayseri Education and Research Hospital
Enrollment: 60
Locations: 1
Primary Endpoint: Urine N- telopeptide levels in Pregnant Women with Hyperemesis Gravidarum
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of the study is to determine whether maternal bone resorption would be seen in Hyperemesis Gravidarum and could be detected in early period using serum vitamin D levels, serum calcium (Ca) levels, serum parathormone (PTH) levels and urine N- telopeptide levels in the patients with Hyperemesis Gravidarum.

Registry

clinicaltrials.gov

Start Date

June 2016

End Date

October 2016

Last Updated

9 years ago

Study Type

Observational

Sex

Female

Investigators

Sponsor

Kayseri Education and Research Hospital

Responsible Party

Principal Investigator

Erdem Sahin

Principal Investigator

Kayseri Education and Research Hospital

Eligibility Criteria

Inclusion Criteria

•weeks of gestation pregnant women in both groups
•İn hyperemesis group; 5% weight loss with regard to pre-gestation vomiting more than 3 times 3-5 % weight loss with ketonuria.

Exclusion Criteria

•Other pathologies that cause nausea and vomiting in pregnancy gastroenteritis gastroparesis gall duct diseases hepatitis peptic ulcers appendicitis pyelonephritis ovarian torsion urinary tract stones diabetic ketoacidosis hyperthyroidism hyperparathyroidism migraine pseudo tumor cerebra vestibular diseases
•Additionally some situations causing to rise of Ntx levels osteoporosis paget disease bone tumors
•Furthermore some of conditions resulted in pre-menopausal osteoporosis or decreasing in Bone Mineral Density Malignancy Smoking Celiac Disease Depression Inflammatory Bowel Disease Pre-gestational Diabetes Chronic Kidney or Liver Disease Drug Use such as steroids, anticonvulsants, antiepileptic, heparin or low molecular weight heparin