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Prospective Study and Analysis of Biomechanical Parameters of Human Movement Based on Disability Indicators in Older Adults

Completed
Conditions
Disability
Interventions
Other: Exposure to disability
Registration Number
NCT05656690
Lead Sponsor
Polytechnic Institute of Porto
Brief Summary

Mobility loss in older people is caused by a variety of aging impairments in various body systems.The disability, which includes physical impairments and resulting activity limitations or participation restrictions, can arise acutely from a catastrophic illness or, more commonly, from subacute functional decline without a clear triggering event. Lower physical functioning was associated with higher healthcare utilization and expenditures, leading to a large burden on government-funded healthcare services. Early identification of mobility changes and intervening in them would likely be the most effective strategy to reduce the burden of disability in the population. Overall, there is a need to develop strategies to reduce disability among older adults in which kinetic and kinematic characteristics are used to predict disability status.

Accordingly, the purpose of this prospective cohort is to identify biomechanical parameters, from the gait, sit-to-stand, timed up and go, stair ascend and descend, and quiet standing functional tasks, as predictors of changes in health and disability status in older adults.

This research was funded by Fundação para a Ciência e Tecnologia (FCT), NORTE 2020, and European Social Fund of European Union, grant number 2020.05356.BD and through R\&D Units funding (UIDB/05210/2020), Fundação para a Ciência e Tecnologia (FCT), Portugal and the European Union.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
60
Inclusion Criteria
  • older adults, 60 years or over;
  • community-dwelling;
  • able to perform the tasks (gait, sit-to-stand, climb and descend stairs) independently;
Exclusion Criteria
  • older adults who are institutionalized;
  • older adults who have established diagnosis of malignancy or terminal diseases with an anticipated survival of less than 1 year;
  • older adults who have stroke history, cerebral hemorrhage, head trauma, or Parkinson's disease;
  • older adults who have cognitive impairment, specifically Mini Mental StateExamination (Portuguese version) score of 22 for 0 to 2 years of literacy, 24 for 3 to6 years of literacy and 27 for more than 6 years of literacy (Morgado et al., 2009);
  • older adults who have rheumatic pathologies that interfere with the tasks performance;
  • older adults who have diabetic foot, lower limb fracture less than 6 weeks, or other related conditions;
  • older adults who have unstable cardiovascular disease, liver or renal function failure;
  • older adults who have a body mass index greater than or equal to 30 kg/m2;
  • older adults who vestibular and/or audition or vision impairments non corrected that influence the performance of tasks;
  • older adults who presence of symptoms at the time of evaluation that influences the participant performance of tasks.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Disability Older AdultsExposure to disabilityDisability Older Adults: older adults with disability indicators
Healthy older AdultsExposure to disabilityHealthy older Adults: older adults without disability indicators
Primary Outcome Measures
NameTimeMethod
Waveform from lower limb joint momentsAssessed once at study entry

Waveform from lower limb joint moments measured in Newton-meter (kgm²/s²)

Waveform from total body energyAssessed once at study entry

Waveform from total body energy measured in joules (J)

Mini-Mental State Examination (MMSE)Assessed at study entry and evaluated every three months until the end of 1 year

MMSE provides a brief screening test that quantitatively assesses the severity of cognitive impairment and documents cognitive changes occurring over time

Waveforms from full-body joint anglesAssessed once at study entry.

Waveforms from full-body joint angles measured in degrees (°)

Waveform from centre of pressure displacementAssessed once at study entry

Waveform from centre of pressure displacement in m/s

Waveform from full-body angular joint velocitiesAssessed once at study entry

Waveform from angular joint velocities measured in degrees per second (°/s)

Waveform from centre of mass displacementAssessed once at study entry

Waveform from centre of mass displacement in m/s

Waveform from lower body joint powerAssessed once at study entry

Waveform from lower body joint power measured in Watts

International Physical Activity QuestionnaireAssessed at study entry and evaluated every three months until the end of 1 year

IPAQ is questionnaire to assess self-reported physical activity

Barthel IndexAssessed at study entry and evaluated every three months until the end of 1 year

The Barthel Index is an instrument that assesses the individual's level of independence for ten activities of daily living

Waveform from full-body separate segment energyAssessed once at study entry

Waveform from body segment energy un joules (J)

Waveform from lower body joint forcesAssessed once at study entry

Waveform from lower body joint forces measured in Newton (N)

Number of fallsAssessed at study entry and evaluated every three months until the end of 1 year

Total number and description of ocurrences of falls

Lawton and Brody Instrumental Activities of Daily Living ScaleAssessed at study entry and evaluated every three months until the end of 1 year

Lawton and Brody Instrumental Activities of Daily Living Scale assess the instrumental ADLs necessary for living in the community

Number of health conditionsAssessed at study entry and evaluated every three months until the end of 1 year

Total number and description of health conditions

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Center for Rehabilitation Research, School of Health, Polytechnic of Porto, Portugal

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Porto, Portugal

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