Study and Analysis of Biomechanical Parameters of Human Movement Based on Disability Indicators in Older Adults Based on a Multifactorial Analysis: a Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Waveform from lower limb joint moments
研究概览
简要总结
Mobility loss in older people is caused by a variety of aging impairments in various body systems.The disability, which includes physical impairments and resulting activity limitations or participation restrictions, can arise acutely from a catastrophic illness or, more commonly, from subacute functional decline without a clear triggering event. Lower physical functioning was associated with higher healthcare utilization and expenditures, leading to a large burden on government-funded healthcare services. Early identification of mobility changes and intervening in them would likely be the most effective strategy to reduce the burden of disability in the population. Overall, there is a need to develop strategies to reduce disability among older adults in which kinetic and kinematic characteristics are used to predict disability status.
Accordingly, the purpose of this prospective cohort is to identify biomechanical parameters, from the gait, sit-to-stand, timed up and go, stair ascend and descend, and quiet standing functional tasks, as predictors of changes in health and disability status in older adults.
This research was funded by Fundação para a Ciência e Tecnologia (FCT), NORTE 2020, and European Social Fund of European Union, grant number 2020.05356.BD and through R&D Units funding (UIDB/05210/2020), Fundação para a Ciência e Tecnologia (FCT), Portugal and the European Union.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •older adults, 60 years or over;
- •community-dwelling;
- •able to perform the tasks (gait, sit-to-stand, climb and descend stairs) independently;
排除标准
- •older adults who are institutionalized;
- •older adults who have established diagnosis of malignancy or terminal diseases with an anticipated survival of less than 1 year;
- •older adults who have stroke history, cerebral hemorrhage, head trauma, or Parkinson's disease;
- •older adults who have cognitive impairment, specifically Mini Mental StateExamination (Portuguese version) score of 22 for 0 to 2 years of literacy, 24 for 3 to6 years of literacy and 27 for more than 6 years of literacy (Morgado et al., 2009);
- •older adults who have rheumatic pathologies that interfere with the tasks performance;
- •older adults who have diabetic foot, lower limb fracture less than 6 weeks, or other related conditions;
- •older adults who have unstable cardiovascular disease, liver or renal function failure;
- •older adults who have a body mass index greater than or equal to 30 kg/m2;
- •older adults who vestibular and/or audition or vision impairments non corrected that influence the performance of tasks;
- •older adults who presence of symptoms at the time of evaluation that influences the participant performance of tasks.
结局指标
主要结局
Waveform from lower limb joint moments
时间窗: Assessed once at study entry
Waveform from lower limb joint moments measured in Newton-meter (kgm²/s²)
Waveform from total body energy
时间窗: Assessed once at study entry
Waveform from total body energy measured in joules (J)
Mini-Mental State Examination (MMSE)
时间窗: Assessed at study entry and evaluated every three months until the end of 1 year
MMSE provides a brief screening test that quantitatively assesses the severity of cognitive impairment and documents cognitive changes occurring over time
Waveforms from full-body joint angles
时间窗: Assessed once at study entry.
Waveforms from full-body joint angles measured in degrees (°)
Waveform from centre of pressure displacement
时间窗: Assessed once at study entry
Waveform from centre of pressure displacement in m/s
Waveform from full-body angular joint velocities
时间窗: Assessed once at study entry
Waveform from angular joint velocities measured in degrees per second (°/s)
Waveform from centre of mass displacement
时间窗: Assessed once at study entry
Waveform from centre of mass displacement in m/s
Waveform from lower body joint power
时间窗: Assessed once at study entry
Waveform from lower body joint power measured in Watts
International Physical Activity Questionnaire
时间窗: Assessed at study entry and evaluated every three months until the end of 1 year
IPAQ is questionnaire to assess self-reported physical activity
Barthel Index
时间窗: Assessed at study entry and evaluated every three months until the end of 1 year
The Barthel Index is an instrument that assesses the individual's level of independence for ten activities of daily living
Waveform from full-body separate segment energy
时间窗: Assessed once at study entry
Waveform from body segment energy un joules (J)
Waveform from lower body joint forces
时间窗: Assessed once at study entry
Waveform from lower body joint forces measured in Newton (N)
Number of falls
时间窗: Assessed at study entry and evaluated every three months until the end of 1 year
Total number and description of ocurrences of falls
Lawton and Brody Instrumental Activities of Daily Living Scale
时间窗: Assessed at study entry and evaluated every three months until the end of 1 year
Lawton and Brody Instrumental Activities of Daily Living Scale assess the instrumental ADLs necessary for living in the community
Number of health conditions
时间窗: Assessed at study entry and evaluated every three months until the end of 1 year
Total number and description of health conditions
次要结局
未报告次要终点
研究者
Juliana dos Santos Moreira
PhD grant student
Polytechnic Institute of Porto