Ayurvedic treatment of Allergic Rhinitis

Phase 2/3

Completed

• Conditions: Allergic Rhinitis

• Registration Number: CTRI/2017/12/010937
• Lead Sponsor: CCRAS

Brief Summary

The very fact that while describing the diseases of nose in Sushruta Samhita, one separate chapter has been devoted to *Pratishyaya* in Uttartantra iterates the importance of the same; classified into five types on the pathological basis viz. *Vataja*, *Pittaja*, *Kaphaja*, *Raktaja* and *Sannipataja*. Though it has been said that the disease *Pratishyaya* in the initial phase, is a curable entity, in chronic course it may lead to *Dushta* *Pratishyaya* and then present with many associated complications with changed prognosis as well.

On the basis of clinical features, Ayurvedic scholars today acknowledge to correlate *Vataja* *Pratishyaya* with Allergic Rhinitis (AR), a common ENT problem in modern literature.  Because of being in direct contact with external environment nose is exposed to lot of microorganisms, allergens and environmental pollutants present in the atmosphere.  If this stage is not properly treated, it will cause the mucosal changes in nostrils and result into turbinate hypertrophy, nasal polyps, allergic bronchitis etc.

Allergic rhinitis is also associated with otitis media, Eustachian tube dysfunction, sinusitis, nasal polyps, allergic conjunctivitis, and atopic dermatitis. It may also contribute to learning difficulties, sleep disorders etc.

The lack of curative treatment is necessitating the other health systems to provide a remedial treatment. The world has many expectations from Ayurvedic science in the treatment of AR.As mentioned earlier; AR is very much similar to *Vataja* *Pratishyaya* and as per the Ayurvedic literature, it is a curable disease. One research thesis work was carried out at I.P.G.T. & R.A., Jamnagar with the protocol of *Ashwagandhadi* compound, *Shirishadi Kwatha* and *Anu Taila Nasya*. Significant results were found in this research work. By keeping this fact in mind the same protocol has been proposed here.

Detailed Description

Not available

Study Timeline

• Study Completion: 2017-10-04
• Study Start: 2018-04-16
• Last Update Posted: 2022-02-25

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patients either sex aged between 18 to 65 years.
• Clinical diagnosis persisting symptoms of Allergic rhinitis, X-ray (PNS), Nasal endoscopy and laboratory investigations etc.
• Able and willing to participate and provide signed informed consent.

Exclusion Criteria

• 1.History of chronic nasal or upper respiratory tract symptoms or disorders other than allergic rhinitis.
• 2.History of non allergic rhinitis, chronic sinusitis or serve asthma.
• 3.Patients with nasal anatomical defects (deviated nasal septum).
• 4.Patients with acute episodes i.e. fever/earache/headache.
• 5.Patients with associated tonsillitis or airway obstructions (adenoids).
• 6.Has a nasal condition likely to affect the outcome of the study.
• Corticosteroids Nasal drops, Leukotriene antagonists, Nasal vasoconstrictors.
• 8.Pregnant ladies and Lactating mothers.
• 9.Patients suffering from any debilitating chronic disease like tuberculosis, Uncontrolled Diabetes mellitus 10.Any unstable cardio-vascular diseases 11.Patients with evidence of malignancy.
• 12.Patients with concurrent hepatic disorder (defined as Aspartate Amino Transferase (AST) and / or Alanine Amino Transferase (ALT) > 2 times upper normal limit or Renal Disorders (defined as S.
• creatinine> upper limit of Lab.
• value), Pulmonary Dysfunction (Bronchial Asthma and / or Chronic Obstructive Pulmonary Disease [COPD]) 13.Patient has an acute mental disorder 14.Patients who are currently participating in any other clinical trial.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the effect of Ayurvedic formulation in terms of Control of Allergic Rhinitis and Asthma Test	one month

Secondary Outcome Measures

Name	Time	Method
Not applicable	Not applicable

Trial Locations

Locations (2)

CARICD New Delhi and Safadarjung Hospital Delhi; 🇮🇳 Delhi, DELHI, India

RRAP Central Ayurveda Research Institute for Cancer; 🇮🇳 Mumbai, MAHARASHTRA, India

CARICD New Delhi and Safadarjung Hospital Delhi

🇮🇳Delhi, DELHI, India

Dr Mata Shweta

Principal investigator

8866014946

shwetamatadr@gmail.com