Exercise Therapy in Cancer Patients Who Are Recovering From COVID-19
- Conditions
- CancerCovid19Coronavirus
- Interventions
- Other: Aerobic Exercise Therapy
- Registration Number
- NCT04824443
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Brief Summary
The purpose of the study is to evaluate the safety and tolerability of a 30-week aerobic exercise therapy program in cancer patients recovering from COVID-19. The study will look at whether the aerobic exercise therapy causes few or mild side effects in participants. Aerobic exercise is physical activity that uses the large muscle groups (muscles in your legs, buttocks, back, and chest) and can be performed for several minutes at a time. The aerobic exercise therapy being used in this study will be a walking program that will be adjusted so it matches participant fitness levels (how much exercise you can handle).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 3
-
Age ≥ 18
-
Previously admitted to a hospital for Covid-19
-
Discharged from hospital for at least 30 days
-
Previously treated for cancer at MSK
-
Interval of ≥ 12 months but ≤ 10 years following completion of primary non-hormonal anti-cancer therapy (current endocrine therapy and maintenance therapy allowed)
-
Space to house a treadmill at personal residence
-
Cleared for exercise participation as per screening clearance via the Physical Activity Readiness Questionnaire (PAR-Q+)
-
Performing less than 90 minutes of structured moderate-intensity or strenuous-intensity exercise per week, as evaluation by self-report
-
If a female of child-bearing potential, must not be pregnant or planning to become pregnant during the study.
- Women <50 years old who are of child-bearing potential must have a negative pregnancy test within 14 days of enrollment.
- Currently receiving home oxygen after discharge
- Enrollment onto any other interventional investigational study
- Current treatment for any other diagnosis of invasive cancer of any kind
- Distant metastatic malignancy of any kind
- Receiving non-hormonal anticancer therapy
- Any other condition or intercurrent illness that, in the opinion of the investigator, makes the subject a poor candidate for study participation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Participants who were hospitalized for COVID-19 Aerobic Exercise Therapy Participants will be post-cancer treatment patients who were hospitalized for COVID-19.
- Primary Outcome Measures
Name Time Method Frequency of serious adverse events during study-related assessments 30 weeks Safety will be evaluated by the frequency of serious (i.e., life-threatening, hospitalization, significant incapacity, important medical events) adverse events during study-related assessments and exercise sessions according to the Common Terminology Criteria for Adverse Events (CTCAE) v5.0.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (7)
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
🇺🇸Montvale, New Jersey, United States
Memorial Sloan Kettering Monmouth (Limited protocol activities)
🇺🇸Middletown, New Jersey, United States
Memorial Sloan Kettering Cancer Center @ Suffolk - Commack (Limited Protocol Activities)
🇺🇸Commack, New York, United States
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
🇺🇸Basking Ridge, New Jersey, United States
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
🇺🇸Uniondale, New York, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
🇺🇸New York, New York, United States
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
🇺🇸Harrison, New York, United States