Effect Of Exercise Training In Patients With Lung Cancer During Chemotherapy Treatment
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Lung Cancer, Nonsmall Cell
- Sponsor
- Riphah International University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- 6 min walk test: Distance (meters)
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
To determine the effects of exercise training in patients with lung cancer during chemotherapy treatment. In currently accessible literature, majority studies, met-analysis, and systemic reviews are related to surgical procedures and post-op pulmonary Rehabilitation of patients with Lung cancer. In literature, Gap related to the control group was observed also. The current study aimed to fulfill this gap by planning a structured intervention plan for the control group as well. It will also add in literature the deficiency of oncology rehab for patients receiving chemotherapy only.
Detailed Description
Literature suggested that a pulmonary rehabilitation program for patients with non-small cell lung cancer undergoing induction chemo-radiotherapy seems to improve respiratory function. It is particularly recommended for smokers and patients with respiratory impairment.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Diagnosed patients of stage 1 and 2 Non-small cell lung carcinoma (NSCLC) including Adenocarcinoma \& squamous cell carcinoma The diagnosis was established within 6 wk prior to enrollment and was confirmed by histology.
- •Participants are undergoing lung cancer chemotherapy Participant has the willingness to participate in training WHO physical fitness scores 0-1 Able to perform 6-minute walk test (6MWT) at baseline
Exclusion Criteria
- •• Participant with history of trauma and surgery
- •Patients with lung disease other than lung cancer
- •Uncontrolled hypertension or unstable coronary artery disease.
- •Severe OA, bone or CNS metastases.
- •hemoglobin \<10 g/dL
- •Lower than 3,500 white blood cells per microliter of blood
Outcomes
Primary Outcomes
6 min walk test: Distance (meters)
Time Frame: 4 weeks
Changes from the baseline, 6 min walk test (6 MWT) was used to measure Functional capacity. It is a sub maximal exercise test which can aid in assessing functional capacity of patients with cardiopulmonary diseases, in this test we find out the maximum distance in meters which an individual covers in 6 min without any support.
Forced Expiratory Volume in 1 second (FEV1)
Time Frame: 4 weeks
Changes from the Baseline, the digital spirometer is used in clinical setting to analyze Forced Expiratory Volume in 1 second FEV1 in Liters
Forced vital Capacity (FVC)
Time Frame: 4 weeks
Changes From the Baseline, the digital spirometer is used in clinical setting to analyze Forced vital Capacity in Liters
Rate of perceived exertion (RPE)
Time Frame: 4 weeks
Changes From the Baseline, measured through Borg RPE scale which measures a person's perception of their effort and exertion breathlessness, and fatigue during physical work rating between 1 and 10. The higher the number, the more intense the exercise. An RPE of 1 is often referred to as just above rest, hardly any exertion, while an RPE of 10 is a maximal effort.
Secondary Outcomes
- Hospital Anxiety and Depression(4 weeks)
- Mindfulness(4 weeks)