Effectiveness of intravenous dexamethasone plus adductor canal block vs adductor canal block alone to prolong analgesia following total knee arthroplasty: A randomized controlled trial

Phase 4

Recruiting

• Conditions: Patients undergoing elective unilateral TKA; OA knee; TKA; Adductor canal block; Pain score; Morphine consumption

• Registration Number: TCTR20240428001
• Lead Sponsor: Rayong Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-04-28
• Last Update Posted: 19 August 2024
• Study Completion: 2025-02-01

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

1.Aged 55-80 years with ASA class of I-III scheduled to undergo primary unilateral elective TKA
2.Gave informed consent to participate
3.non DM patient
4.body mass index of 18 -40 kg/m2

Exclusion Criteria

1.Cognitive functional impairment
2.Contraindication for neuraxial anesthesia and peripheral anesthesia
3.Severe kidney or liver disease
4.Allergic to or contraindication for any of the study drugs
5.Chronic opioid use
6.Receive systemic steroid within 3 months before surgery

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
TIme to first analgesic request Postoperative period Hour

Secondary Outcome Measures

Name	Time	Method
Paine score 6,12,18,24 hour postoperation Visual analogue scale,Morphine consumption first 24 hours postoperatively mg