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Effect of 1-year cholecalciferol supplementation from early post-transplant preiod in kidney transplant recipients: a randomized controlled trial

Not Applicable
Conditions
kidney transplantation
Registration Number
JPRN-UMIN000020597
Lead Sponsor
agoya Daini Red Cross Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up continuing
Sex
All
Target Recruitment
193
Inclusion Criteria

Not provided

Exclusion Criteria

1. On supplementation with native vitamin D (i.e., cholecalciferiol or ergocaliferol) 2. Corrected calcium >= 11.0 mg/dL 3. Patients judged to be inappropriate by the physician in charge

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in estimated glomerular filtration rate at 1 year after KTx with adjustment for baseline values
Secondary Outcome Measures
NameTimeMethod
1. Urinary kidney injury biomarkers (i.e., L-FABP and/or urinary protein/creatinine) at 6 months and 12 months after KTx 2. Pathophysiological findings on transplanted kidney at 12 months after KTx 3. Body compositions at 6 months and 12 months after transplantation 4. Bone metabolic markers and bone mineral density at 12 months after KTx 5. Prevalence of the development of hypercalcemia (corrected serum calcium>=11mg/dL) 6. Hospitalization-requiring infection-free survival
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