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Phase II trial of neoadjuvant chemotherapy with XELOX plus Bevacizumab for locally advanced rectal cancer

Phase 2
Conditions
ocally advanced rectal cancer
Registration Number
JPRN-UMIN000003507
Lead Sponsor
agoya Surgical Oncology Group
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
30
Inclusion Criteria

Not provided

Exclusion Criteria

1. Multiple malignacies to be treated 2. Uncontrollable peptic ulcer disease 3. Serious complications 4. Previous history of severe drug-induced allergy 5. Severe neuropathy 6. With interstitial lung disease or pulmonary fibrosis 7. Pregnant 8. Prior chemotherapy with bevacizumab, oxaliplatin or capecitabin 9. Disqualified by attending docor

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Treatment compliance
Secondary Outcome Measures
NameTimeMethod
Overall survival, disease free survival, local recurrence rate, response rate
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