Effect of preload reduction through intermittend hemodialysis or continuous veno-venous hemofiltration on microcirculatory perfusion in patients with chronic kidney failure and critically ill patients - Fluid management and peripheral perfusion

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 40 人开始时间: 待定最近更新: 2024年5月6日

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•We will include two patientspopulations, firstly patients undergoing chronic intermittend renal replacement therapy in an outpatient clinic setting. Secondly we will include patients admitted to the intensive care unit who receive continuous veno-venous hemofiltration with ultrafiltration. Of both populations we will include 20 patients.
•Inclusion criteria for patients receiving chronic intermittend renal replacement therapy:
•- Age above 18 yrs
•- Admitted for intermittend hemodialysis.;Inclusioncriteria for patients admitted to the intensive care unit who receive continuous veno-venous hemofiltration.
•- Age above 18 yrs.
•- Clinical indication for continuous veno-venous hemofiltration with ultrafiltration

•Exclusion criteria for patients receiving chronic intermittend renal replacement therapy:
•- Circumstances making it impossible to perform sublingual measurements, like bleeding of the oral cavity.
•- Patients who require no or only small amounts of ultrafiltration during hemodialysis. ;Exclusioncriteria for patients admitted to the intensive care unit who receive continuous veno-venous hemofiltration.
•- Circumstances making it impossible to perform sublingual measurements, like bleeding of the oral cavity

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