A comparison of Dual triggering versus HCG in poor responders in ART outcomes

Abstract Background The use of dual triggering in high and normal responders accompanied with better IVF cycle outcomes. Also, it has been suggested that dual triggering in poor responders can be accompanied by better results. Objective The aim of present study was to evaluate whether the Dual trigger, can improve oocyte maturation in poor responder patients based on Bologna criteria and their ART outcomes. Materials and methods All poor ovarian responder's patients underwent GnRH antagonist controlled ovarian hyperstimulation protocols in ART cycles. The participants' randomizations were done and patients divided into two groups. In the first group, final oocyte maturation was done by 6500 I.U.HCG alone. In the second group, triggering was done with coadministration of 6500 I.U.HCG plus 0.2?mg triptorelin simultaneous (dual trigger). Oocyte retrieval was performed 36?h after triggering through transvaginal ultrasound-guided. Routine IVF/ICSI was performed as appropriate. Results The number of retrieved oocytes, number of mature oocytes (MII), number of fertilized oocytes (2PN), number of embryo formation, number of transferred embryos and embryo quality have not significant differences between the two groups (p?>?0.05). Also, fertilization and implantation rate, chemical and clinical pregnancy did not differ between groups. Conclusion Dual triggering for final oocyte maturation in poor ovarian responders did not improve the number of mature oocytes (MII) and other ART cycle results.