Evaluation of duration of antibiotic prophylaxis for trans rectal prostate biopsy
- Conditions
- Health Condition 1: N429- Disorder of prostate, unspecifiedHealth Condition 2: null- POST TRANS-RECTAL PROSTATE BIOPSY COMPLICATIONS
- Registration Number
- CTRI/2016/06/007012
- Lead Sponsor
- niversity College of Medical Sciences University of Delhi Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
1. All patients aged more than 40 to 80 years in whom transrectal prostate biopsy was indicated and giving informed consent to participate in the study.
2. Patients with indications for transrectal prostate biopsy (PSA >4ng/ml,abnormal/suspicious DRE,symptoms of prostatism, history of prostate carcinoma in first degree relatives)
1.Patient not willing to give consent for
inclusion in the above study.
2.Patient having active untreated genitourinary
tract infection (prostatitis, cystitis,
Epididymo-orchitis,UTI)
3.Patients with painful, active and untreated
anorectal conditions like untreated proctitis,
fistula in ano, fissure and hemorrhoids
4. Patients with mental disorders or illness who
cannot understand or comply with the study
protocol.
5.Patients with known history of allergy to ciprofloxacin therapy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To assess positive Urine culture rate in both groups following TR prostate biopsy. <br/ ><br>2. To assess pyuria rate in both groups following TR prostate biopsy. <br/ ><br>3. To assess hospitalization rates following TR prostate biopsy. <br/ ><br>4. To assess positive urine culture rate among two groups.Timepoint: Day 1,2 and 5
- Secondary Outcome Measures
Name Time Method 1. To evaluate pain(VAS score) in patients post TR prostate biopsy . <br/ ><br>2. To evaluate post TR prostate biopsy hematuria in patients. <br/ ><br>3. To evaluate the bacterial spectrum and antimicrobial sensitivity spectrum of rectal flora in patients undergoing TR prostate biopsy <br/ ><br>4. To look for any side effect associated with ciprofloxacin therapy in patients post TR prostate biopsy. <br/ ><br>Timepoint: Day 3 and 5