To study the difference between administration of intravenous antibiotics versus intravenous antibiotics plus antibiotics at the incision site to prevent the surgical site infections.
Phase 3
- Registration Number
- CTRI/2024/01/061237
- Lead Sponsor
- Dr Karthikeyan P
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients giving consent to take part in the study.
Patients undergoing clean open abdominal surgeries including inguinal hernia, umbilical hernia and para-umbilical hernia repairs.
Exclusion Criteria
Age of the patient less than 18 years
Age more than 80 years
Laparoscopic surgery.
Patient with type 2 Diabetes mellitus.
Patient with known history of immunodeficiency.
Patient with history of taking systemic corticosteroid therapy.
Presence of pre-existing systemic or local infection.
Patients with strangulated or obstructed hernia.
Patients developing hypersensitivity reaction for the antibiotic.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the effect of combining preoperative intra-incisional administration of antibiotic with intravenous antibiotic in prevention of surgical site infections.Timepoint: Post operative day 3 and then alternative day until suture removal
- Secondary Outcome Measures
Name Time Method To compare the efficacy of preoperative combined intravenous and intra-incisional antibiotic administration with intravenous alone in prevention of Surgical site infections in abdominal surgeries.Timepoint: Post operative day 3 and then alternative day until suture removal