Mechanisms of Mindfulness for Smoking Cessation
Not Applicable
Completed
- Conditions
- Smoking Cessation
- Registration Number
- NCT02943499
- Lead Sponsor
- Brown University
- Brief Summary
The purpose of this study is to understand brain mechanisms of app-based mindfulness training in smokers ages 21 to 65 years.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
- 21-65 years of age
- Smoke 10+ cigarettes/day
- < 3 months abstinence in the past year
- Have a smartphone; and motivated to quit smoking
- Score >18 of 20 on Action subscale of the Readiness to Change Questionnaire
Exclusion Criteria
- Any usage of psychotropic medication: not on a stable dosage 6+ months
- Prior participation in a mindfulness course or regular meditation practice (>20 min/week)
- Serious psychiatric, cognitive, or medical disorder
- MRI contraindications
- Structural brain damage as well as other brain abnormalities revealed by the MRI
- Claustrophobia
- Not being fluent in English
- Recreational drug use
- Pregnant women
- History of a neurological disorder
- Current participation in a smoking study
- Adults unable to consent
- Prisoners
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Change From Baseline in Blood Oxygen Level Dependent (BOLD) Signal 1 month BOLD signal change will be measured by fMRI and analyzed using statistical parametric mapping
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What neural pathways are modulated by app-based mindfulness training in smoking cessation (NCT02943499)?
How does smartphone-delivered mindfulness compare to varenicline in relapse prevention for nicotine dependence?
Which biomarkers (e.g., cortisol, brain connectivity) predict response to mindfulness interventions in adult smokers?
What adverse events are reported in digital mindfulness programs for smoking cessation and how are they managed?
Can mindfulness training apps be combined with pharmacotherapy (e.g., bupropion) for enhanced smoking cessation outcomes?
Trial Locations
- Locations (1)
University of Massachusetts, Worcester
🇺🇸Worcester, Massachusetts, United States
University of Massachusetts, Worcester🇺🇸Worcester, Massachusetts, United States