Effects of lung expansion manoeuvres compared to standard physical therapy of adult subjects receiving mechanical ventilation: A randomized controlled clinical trial

Not Applicable

• Conditions: Pulmonary collapse; hypoventilation; Extreme obesity with alveolar hypoventilation

• Registration Number: RBR-7nd6kcb
• Lead Sponsor: niversidade Federal de Juiz de Fora

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-10-07
• Study Completion: 2022-12-30
• Last Update Posted: 26 June 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Participants aged 18 or over will be included; on mechanical ventilation between 12 and 48 hours; not participating in a palliative care program.

Exclusion Criteria

Hemodynamic instability (heart rate > 130 bpm and/or mean arterial pressure < 60mmHg); severe bronchospasm; undrained pneumothorax; pulmonary hemorrhage; thoracic trauma; thoracic surgery performed in the last 24 hours; patients transferred to another hospital.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Expected primary outcome 1: Evaluate the increase in the value of static lung compliance after the intervention, verified by performing an inspiratory pause during mechanical ventilation and the result of the tidal volume divided by the plateau pressure minus the positive end-expiratory pressure, from an increase of at least 10% in measurements at 4 (four) time points: initial assessment, after the standard protocol, after the intervention and 30 minutes after the intervention. Metric: ml/cmH2O