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An exploratory intervention study of renal rehabilitation for patients with conservative chronic kidney disease

Phase 2
Recruiting
Conditions
chronic kidney disease
proteinuria
D051436
Registration Number
JPRN-jRCT1030220165
Lead Sponsor
Aizawa Masashi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
12
Inclusion Criteria

1) Age 20 or older at the time consent is obtained
2) Male or female resident in Japan
3) Inpatient or outpatient: outpatient
4) Patients who meet the criteria for chronic kidney disease
5) Urine protein level of 1 g/gCre or more for two consecutive urine tests at any time in an outpatient setting.
6) Independent in activities of daily living (ADL) (including walking with a cane)
7) Patients who can give written consent for participation of their own free will
8) Patients who understand and can perform the training on their own.

Exclusion Criteria

1) Patients who cannot give their consent
2) Patients on dialysis or renal transplant patients
3) Patients with eGFR (Cre) less than 8 or requiring dialysis induction within 3 months
4) Medically unstable patients (uncontrolled hypertension (blood pressure > 180/100 mmHg), congestive heart failure, active myocarditis/pericarditis, arrhythmia, etc.)
5) Patients with impaired mobility due to mental and physical problems
6) Patients who have participated in a structured exercise program within the past 6 months
7) Patients taking steroids
8) Patients who are deemed unsuitable as subjects by the principal investigator (subinvestigator)

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in urinary protein
Secondary Outcome Measures
NameTimeMethod
Change in 6-minute walk distance, cardiac function (left atrial strain)<br>Change in eGFR (Cre, Cys-C), presence of adverse events
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