An explorative and experimental study to assess the feasibility, acceptability and effectiveness of four imagery intervention techniques in the treatment of auditory vocal hallucinations

Completed

• Conditions: Auditory vocal hallucinaties; hearing voices; 10037176

• Registration Number: NL-OMON53589
• Lead Sponsor: GGZ Eindhoven (Eindhoven)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 32

Inclusion Criteria

• Age 16-65 • Experiencing subclinical or clinical psychotic auditory vocal
hallucinations as confirmed by a clinician and as indicated by an intensity
score of 4 or more on subscale 1.3 (perceptual abnormalities) of the
Comprehensive Assessment of At Risk Mental States (CAARMS; Yung et al., 2005)
or as indicated by a score of 3 or more on item P3 (hallucinatory behavior) of
the Positive and Negative Syndrome Scale (PANSS; Kay, Fiszbein, & Opler,
1987). • A DSM-5 (APA, 2013) diagnosis in the psychosis spectrum (codes: DSM-5
codes: 297.1; 298.8; 295.40; 295.90; 295.70; 298.8; 298.9) or defined as Ultra
High Risk/At Risk Mental State (ARMS or UHR) according to the CAARMS estimated
by a clinician.

Exclusion Criteria

• Any current or previous neurological disorder or organic brain disease. •
Acute confusional state or delirium not caused by the psychotic disorder. •
Unwillingness to participate • IQ < 70 estimated by clinician. • Current
severe substance or alcohol misuse impacting treatment (clinicians assessment).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome variables are the level of auditory vocal hallucinations,<br /><br>imagery characteristics (imagery frequency, imagery appraisals and imagery<br /><br>quality) measured three times a day using a diary method, and feasibility and<br /><br>acceptability measures (adverse (side) effects, drop-out rates and qualitative<br /><br>review of therapy). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary outcomes are the level delusions, visual hallucinations and<br /><br>social and occupational functioning measured three times a day using a diary<br /><br>method.</p><br>