Rhythm Experience and Africana Culture Trial
- Conditions
- Cognitive PerformanceBrain Structure
- Interventions
- Behavioral: African DanceBehavioral: African Cultural Immersion
- Registration Number
- NCT03771716
- Lead Sponsor
- University of Pittsburgh
- Brief Summary
REACT is a randomized intervention to examine the benefits of African Dance as a method to increase physical activity behaviors in older adults. In this 6- month intervention, older African Americans will be randomly assigned to either an African Dance or an Africana Culture class. Both before and at the completion of the intervention, the investigators will collect a comprehensive neuropsychological battery and MRI scans of brain health and function to better study how physical activity influences neurocognitive health in African Americans.
- Detailed Description
Aim 1: Examine whether the African Dance intervention improves cognitive performance compared to an educational control group. H1: The dance group will show cognitive improvements in a domain-specific fashion such that executive and memory functions will be enhanced more than other cognitive domains; Aim 2. Examine whether African Dance influences brain morphology, task-evoked neural responses, cerebral blood flow, and resting state connectivity. H1: It is predicted that African Dance will increase volume, white matter integrity, perfusion, and functional activation/connectivity in a regionally-specific fashion such that prefrontal and hippocampal areas will be more sensitive to the intervention than other brain regions. Aim 3. Explore potential physiological and socio-emotional mechanisms of the dance intervention. The investigators will collect measures of physical and psychosocial health such as waist circumference, blood pressure, blood glucose and lipid levels, mood, anxiety, depression, and loneliness and examine whether intervention-related changes to these measures mediate improvements in cognitive performance.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 151
- self identifies race as African American
- between 60 and 80 years of age
- ambulatory without pain or the assistance of walking devices
- no history of falls or balance problems
- able to speak and read English
- available during the times classes are offered and able to make at least 80% of classes (e.g., no long-term travel plans)
- reliable means of transportation
- scores above the range on the Brief Telephone Interview for Cognitive Status (TICS) indicative of moderate to severe cognitive impairment (scores 21 or above)
- no diagnosis of a neurological disease or psychiatric conditions
- eligible to undergo MRI (not claustrophobic and no metal or history of injury involving metal).
- Fully vaccinated for COVID-19.
- self identifies race as other than African American
- not between 60 and 80 years of age
- not ambulatory without pain or the assistance of walking devices
- history of falls or balance problems
- unable to speak and read English
- unavailable during the times classes are offered or unable to make at least 80% of classes (e.g., indicates long-term travel plans during intervention period)
- no reliable means of transportation
- scores in range on the TICS indicative of moderate to severe cognitive impairment (scores 21 or below)
- has a diagnosis of a neurological disease or psychiatric condition
- ineligible to undergo MRI (claustrophobic and/or metal in body or history of injury involving metal).
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description African Dance African Dance This is the experimental group. Dance classes will be held 3 times per week for 1 hour. Participants will learn traditional Africana dance moves and sequences. African Cultural Immersion African Cultural Immersion This is the active control group. Participants will participate in a variety of educational activities related to African Culture, including traditional cooking, lectures, crafts, music and films. They will meet 3 times per week for the same duration as the Dance group. However, they will not participate in aerobic activity during the classes, and most activities will be conducted in a seated position.
- Primary Outcome Measures
Name Time Method Flanker Performance Changes from baseline to 6-months A Flanker task will be administered at baseline, and then following the intervention (6-months). The main outcome from this task an interference effect (in ms) which indicates how much longer it takes for a participant to make a directional response to a center arrow when the flanking arrows are arranged in congruent vs. incongruent direction from the center stimulus. A higher interference effect indicates worse executive functioning. Group differences will be tested on this outcome.
- Secondary Outcome Measures
Name Time Method Hippocampal volume (mm3) Changes from baseline to 6-months Structural scans will be collected at baseline as well as following the intervention. Hippocampal volume will be calculated in mm3. The investigators will examine group differences in size of the hippocampus following the intervention.
Trial Locations
- Locations (1)
University of Pittsburgh
🇺🇸Pittsburgh, Pennsylvania, United States