Blood pressure profile in patients with a thoracic aortic aneurysm (TAA) or dissection (TAD) under various physical training conditions

Conditions: I71.0
I71.1
I71.2
I71.5
I71.6
Dissection of aorta [any part]
Thoracic aortic aneurysm, ruptured
Thoracic aortic aneurysm, without mention of rupture
Thoracoabdominal aortic aneurysm, ruptured
Thoracoabdominal aortic aneurysm, without mention of rupture

Registration Number: DRKS00027639

Lead Sponsor: Professur für Rehabilitationsmedizin, Fakultät für Gesundheitswissenschaften Brandenburg, Universität Potsdam

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 42

Inclusion Criteria

age: 18-65 years;
exposed group: patients with a thoracic aortic aneurysm (TAA) or dissection (TAD);
control group: healthy staff of the clinic

Exclusion Criteria

no consent to participation;
pacemaker;
load-limiting neurologic, orthopaedic or muscular comorbidity;
obesity (BMI > 39 kg/m^2);
postcardiotomy syndrome;
unstable angina pectoris;
renal insufficiency (GFR < 30 ml/min/1,73m^2);
severe liver diseases;
NYHA classification III/IV or left ventricular ejection fraction < 20%;
lung disease with reduced oxygen consumption (SpO2 < 90%);
language or understanding barriers (e.g. dementia);
diagnosed addiction (e.g. alcohol abuse)

Study & Design

Study Type: observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
blood pressure under physical exercise conditions, one-time, SOMNOtouchNIBP (SOMNOmedics GmbH, CE-identification 0297, Randersacker, Germany)

Secondary Outcome Measures

Name	Time	Method
heart rate, the oxygen saturation in the blood, the mean arterial pressure, and the heart rate variability during physical exercise conditions, one-time, SOMNOtouchNIBP (SOMNOmedics GmbH, Randersacker, Germany)<br>Patients: questionnaires about anxiety and depression (HADS-D), the health-related quality of life (SF-12), and questions about their occupation, measurement time point, and 6 months later