A Computer-based Memory Strategy Training Program to Promote Everyday Performance in Healthy Older Adults, Older Adults With Memory Complaints, Mild Cognitive Impairment and Mild Dementia
Trial Snapshot
- Phase
- Not Applicable
- Status
- Suspended
- Enrollment
- 60
- Locations
- 3
- Primary Endpoint
- Accceptability
Study Overview
Brief Summary
A computer-based cognitive rehabilitation program based on daily tasks utilising the semantic or perceptual encoding strategies called Enhancing Memory in Daily Life (E-MinD Life) has been developed for Chinese people. The aim of the E-MinD Life is to delay functional deterioration associated with possible cognitive changes in healthy older adults, older adults with memory complaints, mild cognitive impairment (MCI) and mild dementia. This project will pilot-test the E-MinD Life in Chinese healthy older adults, older adults with memory complaints, MCI and mild dementia.
Detailed Description
The objectives of the study are to investigate the feasibility and pilot-test the benefits of the computer-based E-MinD Life (Semantic) or (Perceptual) program to promote everyday performance in healthy older adults, older adults with memory complaints, mild cognitive impairment (MCI) and mild dementia in Hong Kong using a randomised control trial.
Three groups of participants will be recruited: (1) 15 healthy older adults, (2) 15 older adults aged over 65 years with memory complaints, or older adults aged over 65 years, meeting the diagnostic criteria for MCI with a Clinical Dementia Rating score of 0 or having mild dementia with a Clinical Dementia Rating score of 1. All participants will have no depression and other clinical conditions that may affect their cognition. Their scores on the Montreal Cognitive Assessment will be recorded. Their carers or family members are invited to participate.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Ages
- 65 Years to — (Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Group 1: healthy older adults aged 65 years or above Group 2: older adults aged 65 years or above with memory complaints Group 3: older adults aged 65 or above with mild cognitive impairment
Exclusion Criteria
- •(for all groups 1, 2 and 3)
- •- have depression and other clinical conditions that may affect their cognition.
Arms & Interventions
Cognitive stimulation
Participants will receive cognitive stimulation.
Intervention: Cognitive stimulation (Behavioral)
E-MinD Life
Participants receive the E-MinD Life (Semantic or Perceptual) programme.
Intervention: E-MinD Life Semantic (Behavioral)
Outcomes
Primary Outcomes
Accceptability
Time Frame: End of the intervention at 9 weeks
Acceptability is measured using a structured questionnaire divided into five sections: (1) the therapist-led group sessions, (2) the self-administered individual sessions, and (3) the computer program interface and iPad usability, (4) the overall program design and structure and (5) overall satisfaction. Participants are invited to give quantitative ratings on four dimensions under each section: (a) perceived effectiveness (e.g., whether the program improved cognitive strategy use), (b) relevance (e.g., how applicable the activities were to daily life), (c) convenience (e.g., ease) and (d) clarity. Responses are collected using a 4-point Likert scale, ranging from 1 "Completely disagree" to 4 "Completely agree," with higher scores indicating greater acceptability.
Secondary Outcomes
- Feasibility by measuring the attendance rate(Through the intervention for 9 weeks, attendance at each session)
- Consortium to Establish a Registry for Alzheimer's Disease - Neuropsychological Assessment Battery (CERAD-NAB)(From enrollment to the end of intervention at 9 weeks)
- Digit Span Test(From enrollment to the end of intervention at 9 weeks)
- Lawton Instrumental Activities of Daily Living Scale(From enrollment to the end of intervention at 9 weeks)
- Disability Assessment for Dementia (DAD)(From enrollment to the end of intervention at 9 weeks)
- EuroQoL- 5 Dimensions - 5 Levels Hong Kong version (EQ-5D-5L_HK)(From enrollment to the end of intervention at 9 weeks)
Investigators
LIU Karen
Professor
The Hong Kong Polytechnic University