The effect of moderate acidification of arterial blood pH by controlled inhalation of carbon dioxide on the rate of reperfusion injury in the early minutes after aortic clamp opening during heart valve surgery: A Pilot Study
Not Applicable
- Conditions
- The effect of moderate arterial blood acidosis during reperfusion in valvular heart surgery.Endocarditis, valve unspecified
- Registration Number
- IRCT20211101052940N1
- Lead Sponsor
- Shahid Rajaei Cardiovascular Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Patient consent to study
Age over 18 years and under 65 years
No history of sternotomy and heart surgery
Left ventricular ejection fraction greater than 30%
Pulmonary outflow volume with pressure per second (FEV1) greater than 65% in spirometry
Hemoglobin above 10 mg per deciliter
Exclusion Criteria
Need for drug support (receiving inotropes before starting heart surgery)
Having a pacemaker or ICD(Implantable Cardioverter Defibrillator)
Having impaired lung function tests for FEV1 less than 40%
Having kidney or liver dysfunction
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method